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Novel Potentiators of Fluoroquinolones for Gram-negative Pathogens

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Award date: 
Jun 14, 2012
Award amount: 
Organization name: 
UNC - Chapel Hill
Principal Investigator: 
Singleton, Scott F.
Grant program category: 
Research and Equipment Support
Grant program name: 
Collaborative Funding Grant
Research Triangle

Synereca Pharmaceuticals has identified small molecule inhibitors of DNA repair that enhance killing by fluoroquinolone antibiotics. Synereca will develop these inhibitors and demonstrate their utility in crucial in vivo infection models. The pharmacologic proof of concept will enhance Synereca's ability to attract partners and investors.

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