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Novel Potentiators of Fluoroquinolones for Gram-negative Pathogens

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Award date: 
Jun 14, 2012
Award amount: 
Organization name: 
UNC - Chapel Hill
Principal Investigator: 
Singleton, Scott F.
Grant program category: 
Research and Equipment Support
Grant program name: 
Collaborative Funding Grant
Research Triangle

Synereca Pharmaceuticals has identified small compounds that increase the effectiveness of antibiotics. They will develop these small molecule inhibitors of DNA repair that enhance killing by fluoroquinolone and demonstrate their utility in crucial in vivo infection models. This proof of concept study will enhance Synereca's ability to attract partners and investors.

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