Welcome! This site provides basic links to core laboratory facilities in North Carolina that support research in the life sciences and other biotechnology-related fields of study. These core facilities are located at university, non-profit and commercial research institutions across the state.
All of the core facilities listed below have voluntarily submitted their information and have indicated that their services and/or equipment are open to researchers outside of their home institution. Not all institutions list available core laboratory facilities, however, many are in the process of organizing and compiling these resources. As this information becomes available, additional links will be added to this page.
The Biotechnology Center has funded many core facilities in the state. However, we do not intend to represent the facilities in any way other than to serve as an impartial portal to this information.
To submit or modify a core facility listing, use the link on the right side of this page. For questions regarding this website, contact Maria Riley (maria_riley@ncbiotech.org) at (919) 549-8849.
- View core facilities by region:
- For detailed information, view the core facilities list (PDF)
EASTERN REGION
- DUKE UNIVERSITY MARINE LABORATORY
Marine Conservation Molecular Facility (Beaufort, NC)
The Marine Conservation Molecular Facility (MCMF) is a shared use molecular lab for genetic analysis of marine organisms. The MCMF offers 8 bench spaces, 12 thermal cyclers, 2 real-time thermal cyclers, a pipetting robot, and an ABI Sequencer.
Director/Contact: Tom Schultz, Ph.D.
Tom.Schultz@duke.edu or (252) 504-7641
http://www.nicholas.duke.edu/marinelab/facilities/mcmf
- EAST CAROLINA UNIVERSITY, BRODY SCHOOL OF MEDICINE
Laser Capture Microdissection Core Laboratory (Greenville, NC)
The Zeiss PALM Laser Capture unit is located at the Brody School of Medicine. ECU provides instrumentation, facilities for preparing and staining both frozen/paraffin sections, and limited assistance in obtaining samples for DNA or RNA.
Director: Barbara Muller-Borer, Ph.D.
Contact: Cindy Kukoly
kukolyc@ecu.edu or (252) 744-2962
http://www.ecu.edu/cs-dhs/internalmed/lasercapture/
GREATER CHARLOTTE REGION
- CAROLINAS MEDICAL CENTER
Cannon Research Center Core Facilities (Charlotte, NC)
The Cannon Research Center has many core facilities including those for biostatistics, comparative medicine, confocal mircroscopy, electron microscopy, flow cytometry, histology, mass spectrometry and proteomics, molecular biology, and research machining.
Director: Herbert L. Bonkovsky, MD
Contact: Dhanonjoy C. Shaha, DVM, Ph.D.
Dhanonjoy.Saha@carolinashealthcare.org or (704) 355-5383
http://www.carolinasmedical center.org/body.cfm?id=1541
- NORTH CAROLINA RESEARCH CAMPUS
David H. Murdock Research Institute (Kannapolis, NC)
The world’s most powerful technologies have been integrated into a cohesive and comprehensive research system with state-of-the-art capabilities in one central location. Services are provided in genomics, proteomics, metabolomics, microscopy, and NMR.
Director: Michael Luther, Ph.D., MBA
Contact: Sheetal Ghelani, Ph.D.
sghelani@dhmri.org or (704) 250-2648
http://www.dhmri.org
PIEDMONT TRIAD REGION
- UNIVERSITY OF NORTH CAROLINA CENTER FOR DESIGN INNOVATION
Center for Design Innovation (Winston-Salem, NC)
**Partnerships are in formation and inquiries are encouraged.
CDI's goal is to catalyze the growth of creative industries in the Piedmont Triad through design-focused activity based on advanced technologies. Services in rapid prototyping and design in various media are available.
Director/Contact: Carol Strohecker, Ph.D.
cs@centerfordesigninnovation.org or (336) 354-7358
http://www.centerfordesigninnovation.org
- UNIVERSITY OF NORTH CAROLINA GREENSBORO
Biomolecular Simulation and Bioinformatics Core Lab (BSBC) (Greensboro, NC)
The BSBC provides high-performance computing resources to the scientific community (including faculty, scientists, and BioTech/BioPharma companies) in the Piedmont Triad area whose biotechnology research requires high-performance parallel computing.
Director: Patricia H. Reggio, Ph.D.
Contact: Karen C. Burton
bsbc_admin@uncg.edu or (336) 256-8610
http://bsbc.uncg.edu
- WAKE FOREST UNIVERSITY
Wake Forest University Core Laboratory Facilities (Winston-Salem, NC)
WFU is home to many core research facilities which include microscopy, X-ray, NMR, and computer facilities; biomechanics, human performance, blood chemistry, physical function and behavioral physiology laboratories; and a Center for Nanotechnology.
http://www.wfu.edu/academics/research/
RESEARCH TRIANGLE REGION
- ALMAC DIAGNOSTICS
Almac Diagnostics Molecular Core Lab (Durham, NC)
Personalized medicine company offering the following genomics based services: Nucleic acid extraction, mRNA, microRNA and DNA expression profiling, Bioinformatics, cell line modeling, and biomarker discovery and validation.
Director: Kimberly Slent-Kesler, Ph.D.
Contact: Kevin Ellison
kevin.ellison@almacgroup.com or (919) 294-0234
http://www.almacgroup.com
- CAMPBELL UNIVERSITY
Campbell University Pharmaceutical Sciences Institute (Buies Creek, NC)
Facility laboratories and Clinical Trial Manufacturing areas meet current Good Manufacturing Practices requirements. Our analytical, microbiology, and formulation development capabilities support sterile, oral, and topical product development.
Director/Contact: William C. Stagner, R.Ph., M.S., Ph.D
stagnerw@campbell.edu or (910) 893-1836
http://campbellpharmacy.net/resources/CUPSI.html
- DUKE UNIVERSITY
Biomolecular Characterization Facility (Durham, NC)
User-operated Aviv 62DS CD Spectropolarimeter with automated titrator, thermoelectric temperature control, simultaneous fluorescence and CD detection. Staff-operated Beckman
XL-A analytical ultracentrifuge for sedimentation equilibrium and velocity.
Director/Contact: Terrence G. Oas, Ph.D.
oas@duke.edu or (919) 684-4363
Duke RNAi Screening Facility (Durham, NC)
**Open to outside users collaborating with Duke investigators.
The DRSF provides infrastructure and expertise for the implementation of RNAi-based technologies, both small and genome scale. We also provide custom high-throughput cell-based assay development.
Director: Mariano Garcia-Blanco, M.D., Ph.D.
Contact: James Pearson, Ph.D.
james.pearson@duke.edu or (919) 613-5132
http://www.genome.duke.edu/cores/rnai/
Shared Materials Instrumentation Facility (Durham, NC)
SMIF provides researchers with access to advanced characterization and clean room fabrication capabilities. SMIF is available to all Duke University researchers and to external users from other universities, government labs, and industry.
Director/Contact: Mark D. Walters, Ph.D.
mark.walters@duke.edu or (919) 660-5486
http://smif.lab.duke.edu/
- EXPRESSION ANALYSIS
Expression Analysis (Durham, NC)
Providing whole genome to focused set gene expression/genotyping assays and sequencing services. Genomic services for clinical trials and research - solutions for whole blood specimens and FFPE tissues, also nucleic acid isolation and bioinformatics.
Director: Steve McPhail
Contact: Karen Michailo
kmichailo@expressionanalysis.com or (919) 287-4277
http://www.expressionanalysis.com
- GENTRIS CORPORATION
Gentris Corporation (Morrisville, NC)
Gentris Corporation is a GLP facility providing genomic and biostorage services to pharmaceutical and biotechnical companies.
Director/Contact: Scott Clark, Ph.D.
clarks@gentris.com or (919) 653-5534
http://www.gentris.com
- KRYOSPHERE, INC. - RTP
Kryosphere (Durham, NC)
The comprehensive solution to any researcher's sample management needs. We offer custom biorepository services; management of clinical trial samples; tracking; stability studies; cryopreservation training; and transportation in a GMP, regulatory compliant environment.
Director: Douglas Baker
Contact: L. Eric Hallman, Ph.D.
ehallman@kryosphere.com or (919) 941-9999 x223
http://www.kryosphere.com
- NORTH CAROLINA STATE UNIVERSITY
Cellular and Molecular Imaging Facility (CMIF) (Raleigh, NC)
The CALS Cellular and Molecular Imaging Facility at North Carolina State University is located in the Department of Plant Biology (4115 Gardner Hall) and contains a number of state-of-the-art light microscopes, including a Zeiss LSM 710 confocal.
Director/Contact: Eva Johannes, Ph.D.
eva_johannes@ncsu.edu or (919) 515-3525
http://www.ncsu.edu//project/cmif-micro/
Genomic Sciences Laboratory (GSL) (Raleigh, NC)
The GSL provides NCSU and other scientific communities with high-throughput DNA sequencing and genotyping, functional genomic assays, protein identiifcation and characterization as well as metabolomics, biochem. profiling and target compound analyses.
Director/Contact: Jennifer Schaff, Ph.D.
jeschaff@ncsu.edu or (919) 513-0738
http://www.gsl.cals.ncsu.edu/
Golden LEAF Biomanufacturing Training and Education Center (BTEC) (Raleigh, NC)
BTEC houses 63,000 GSF of fermentation, cell culture, recovery, purification, and analytical lab space for training NCSU students and industry professionals in bioprocessing. BTEC also offers its capabilities for projects with industry and use by NCSU researchers.
Director: Ruben Carbonell, Ph.D.
Contact: Gary Gilleskie, Ph.D.
gary_gilleskie@ncsu.edu or (919) 515-0176
http://www.btec.ncsu.edu
Laboratory for Advanced Electron and Light Optical Methods (Raleigh, NC)
Light and Electron Microscopy Services
Director/Contact: Michael J. Dykstra, Ph.D.
michael_dykstra@ncsu.edu or (919) 513-6202
http://www.cvm.ncsu.edu/research/laelom
NCSU Flow Cytometry and Cell Sorting Facility (Raleigh, NC)
The laboratory provides instrumentation and assistance for multi-parameter flow cytometric analysis and sorting. It is available for use to all NCSU researchers and to those outside the NCSU community and operates as a by appointment, fee for service lab.
Director: Mary Tompkins, Ph.D.
Contact: Janet Dow
jldow@unity.ncsu.edu or (919) 513-6443
http://www.cvm.ncsu.edu/ccmtr/flocyt.html
- UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL
University of North Carolina at Chapel Hill Core Laboratory Facilities (Chapel Hill, NC)
UNC-Chapel Hill hosts more than 50 core facilities. A wide range of services is provided from analytical chemistry to microscopy to X-ray crystallography among others. Access to services may vary. Contact the individual core facility for more information.
http://research.unc.edu/services/core_facilities.php
SOUTHEASTERN REGION
- UNIVERSITY OF NORTH CAROLINA WILMINGTON
UNCW Center for Marine Science (Wilmington, NC)
The mission of the Center for Marine Science at UNCW is to promote basic and applied research in the fields of oceanography, coastal and wetland studies, marine biomedical and environmental physiology, and marine biotechnology and aquaculture.
Director: Daniel G. Baden, Ph.D.
Contact: Mellissa Dionesotes
dionesotesm@uncw.edu or (910) 962-2330
http://www.uncw.edu/cmsr
WESTERN REGION
- APPALACHIAN STATE UNIVERSITY
Dewel Microscopy Facility (Boone, NC)
We provide light microscopy, laser scanning confocal microscopy, and electron microscopy (TEM & SEM) equipment and technical support to ASU and western North Carolina.
Director/Contact: Guichuan Hou, Ph.D.
houg@appstate.edu or (828) 262-2682
http://www.casmifa.appstate.edu/
Human Performance Laboratory (Boone, NC)
The mission of the ASU Human Performance Laboratory is to investigate the influence of unique plant molecules on age-related loss of muscle mass (sarcopenia), muscle mitochondrial biogenesis, and exercise-induced immune dysfunction and oxidative stress.
Director/Contact: David C. Nieman, Dr. PH
niemandc@appstate,edu or (828) 773-0056
http://www.hles.appstate.edu - NC BIONETWORK BIOBUSINESS CENTER (Asheville-Buncombe Technical Enka Campus)
Natural Products Laboratory (Candler, NC)
The Natural Products Laboratory offers services for medicinal herb manufacturing helping customers meet cGMP and FDA regulations for dietary supplements. We also provide rentable lab space for individuals and companies interested in product research, testing and development.
Director/Contact: Sarah Schober
sschober@abtech.edu or (828) 254-1921 ext 5845
http://www.naturalproductslaboratory.com