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Small Molecule Targeting of Dual TRP Channels to Attenuate Inflammation and Fibrosis

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Award date: 
Oct 20, 2015
Award amount: 
Organization name: 
Duke University Medical Center
Principal Investigator: 
Liedtke, Wolfgang B.
Grant program category: 
Research and Equipment Support
Grant program name: 
Biotechnology Innovation Grant
Research Triangle

Small-molecule compounds will be developed for treatment of atopic dermatitis and skin thickening/scarring, which are in need of improved treatments. This will be targeted through ion-channels (TRPV4 & TRPA1) which are based on existing anti-TRPV4/TRPA1 compounds that the Liedtke-Lab has developed.

Fiscal year: