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Neuroprotective pentapeptide improves outcome after ischemic stroke and subarachnoid hemorrhage

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Award date: 
Jun 16, 2014
Award amount: 
$100,000
Organization name: 
Duke University Medical Center
Principal Investigator: 
Laskowitz, Daniel T.
Grant program category: 
Research and Equipment Support
Grant program name: 
Collaborative Funding Grant
Region: 
Research Triangle

We have developed a small peptide that mimics the binding region of a neuroprotective protein called apoE, readily crosses the blood brain barrier, and improves long term outcome following animal models of brain injury. Here, we propose to study the peptide in the setting of stroke and subarachnoid hemorrage.

Fiscal year: 
2014