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Method for Sorting Pure Pancreatic Beta Cells from Dispersed Human Islets Using a Novel Transient Fluorescent Pre-pro-insulin Reporter

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Award date: 
Nov 21, 2011
Award amount: 
Organization name: 
North Carolina Central University
Principal Investigator: 
Hoffler, Undi
Grant program category: 
Research and Equipment Support
Grant program name: 
Technology Enhancement Grant
Research Triangle

Proposed studies seek to produce viable purified human pancreatic beta-cells from donor pancreatic tissue using a novel fluorescent reporter. This technology will enhance diabetes drug discovery efforts and be an important first-step towards transplantation of competent beta-cells into diabetic patients to restore normal pancreatic insulin secretion.

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