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Glycoengineering of Sialylation Pathway in Tobacco Plants for Expressing Humanized Recombinant Glycoproteins

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Award date: 
Jun 4, 2013
Award amount: 
Organization name: 
North Carolina Central University
Principal Investigator: 
Xie, Jiahua (Jay)
Grant program category: 
Research and Equipment Support
Grant program name: 
Biotechnology Research Grant
Research Triangle

This project is aimed at establishing a stable plant-based platform for expressing humanized glycoproteins that can be used as therapeutic proteins. Proof of concept for in planta glycosylation will be shown using the human erythropoietin gene. This project is expected to lead to an alternative and inexpensive way to produce humanized therapeutics.

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