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Discovery of Novel, Efficacious and Safe Biguanides for the Treatment of Ovarian Cancer

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Award date: 
Jun 2, 2015
Award amount: 
$100,000
Organization name: 
UNC - Chapel Hill
Principal Investigator: 
Bae-Jump, Victoria L
Grant program category: 
Research and Equipment Support
Grant program name: 
Collaborative Funding Grant
Region: 
Research Triangle

Obesity and diabetes are associated with increased risk and worse outcomes for ovarian cancer. Novatarg has discovered novel tissue-selective activators of AMP-activated protein kinase (AMPK) that target both metabolic diseases and cancer, and will collaborate with the gyn-oncologist, Dr. Bae-Jump, to investigate these agents in the treatment of ovarian cancer.

Fiscal year: 
2015