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Bio Defense

NCBiotech’s Bio Defense program probes the connections between North Carolina’s $38 billion defense industry and the life sciences.

You may immediately think of bioterrorism, but North Carolina’s small companies, researchers and military representatives are thinking more broadly: providing vaccines for soldiers; protecting the food supply; and deploying novel technologies that will protect our soldiers and heal those who sustain wounds in battle.

Military and homeland Bio Defense development is a critical need for our nation and is also an area that has application to commercial areas of biosciences. North Carolina has numerous assets and areas of overlap that could provide support for several aspects of this critical need.

The North Carolina Biotechnology Center and our partners are working to develop a strategy that is aimed at increasing defense funding in N.C. by aligning the state's well-recognized strengths in the life science sector with the Department of Defense (DoD) and national security strategic priorities. This initiative is an opportunity for the broader N.C. life science community to bring their innovative technological expertise to bear on critical challenges faced by the military and national security agencies on behalf of our state and country.

What is the North Carolina Biotechnology Center doing in support of Bio Defense?
We are:

  • Providing support for researchers seeking DoD funding

  • Providing support to small businesses with a bio defense life science focus

  • Providing support for university-based research in bio defense

  • Promoting and advertising regional and national bio defense and military healthcare conferences and events

  • Representing N.C. at targeted military and federal bio defense conferences throughout the United States and promoting our state's life science industry

  • Hosting conferences (where military, government, academic and industry experts can network and collaborate) including the 2014 NC Bio Defense Summit, Ebola Conference and Grantsmanship Training

  • Connecting key military, industry and academia partners to promote North Carolina’s bio defense capabilities at the state and federal level

  • Watching and reviewing DoD, Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) announcement solicitations relevant to N.C.’s biotechnology sector

  • Developing a database of North Carolina’s Defense Assets

FY18-FY22 USAMRMC Broad Agency Announcement

The United States Army Medical and Materiel Command's (USAMRMC) mission is to provide solutions to medical problems of importance to the American Service member at home and abroad, as well as to the general public at large. The scope of the effort and the priorities attached to specific projects are influenced by changes in military and civilian medical science and technology, operational requirements, military threat assessments, and national defense strategies. Extramural research and development programs play a vital role in the fulfillment of the objectives established by the USAMRMC. General information on the USAMRMC can be obtained at: The USAMRMC Fiscal Year 18 - Fiscal Year 22 (FY18-FY22) Broad Agency Announcement (BAA) is intended to solicit extramural research and development ideas.

The FY 17-FY22 USAMRMC BAA is continuously open for a 5-year period, from October 1, 2017 through September 30, 2022, at 11:59 p.m. Eastern Time. Submission of a pre-proposal/pre-application is required and must be submitted through the electronic Biomedical Research Application Portal (eBRAP). Pre-proposals/pre-applications may be submitted at any time throughout the 5-year period. If the USAMRMC is interested in receiving a full proposal/application, the Principal Investigator will be sent an invitation to submit via eBRAP. A full proposal/application must be submitted through Invited full proposals/applications can be submitted under this FY18-FY22 BAA through September 30, 2022. The FY18-FY22 USAMRMC BAA will be available for download on on October 1, 2017. Search opportunity number: W81XWH18SBAA1

BARDA Issues Three New Board Agency Announcements in Biodefense

The Biomedical Advanced Research Development Authority (BARDA) recently issued three advanced pre-solicitation Broad Agency Announcements (BAAs) for advanced research and development in support of medical countermeasures relative to pandemic influenza, infectious diseases, and chemical, biological, radiological and nuclear (CBRN) threats.

BARDA manages Project BioShield, a program to procure and develop advanced medical countermeasures according to priorities given by national strategies against pandemic flu and CBRN threats. Funding through these BAAs will be evaluated based on relevance to medical countermeasure priorities as presented in the following  publications: 2014 PHEMCE Implementation Plan for CBRN Threats, National Strategy for Pandemic Influenza, 2010 HHS Public Health Emergency Medical Countermeasures Enterprise Review and BARDA Strategic Plan 2011-2016.

Please click on the below links for further information and instructions:

  • BAA-16-100-SOL-00001 - Advanced Research and Development of CBRN Medical Countermeasures
  • BAA-16-100-SOL-00002 - Advanced Development of Medical Countermeasures for Pandemic Influenza
  • BAA-16-100-SOL-00003 - Advanced Research and Development to Expedite the Identification, Development, and Manufacturing of Medical Countermeasures against Infectious Diseases

Business North Carolina magazine, with the help from the North Carolina Biotechnology Center, held a roundtable of distinguished experts discussing opportunities for growing the bio defense sector in N.C.