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Antibody Mediated Targeting of Nanoparticles to MUC1 Expressing Pancreatic Cancer Cells (Hoahiep Nguyen)

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Award date: 
Feb 15, 2013
Award amount: 
Organization name: 
UNC - Charlotte
Principal Investigator: 
Brown, Banita W.
Grant program category: 
Research and Equipment Support
Grant program name: 
Undergraduate Biotechnology Research Fellowship
Greater Charlotte

This research is focused on the development of a nanoparticle-based delivery system for a chemotherapeutic drug conjugated to a cancer-specific antibody (TAB004) for the treatment of pancreatic cancer. The student will assess efficacy by introducing the nanoparticle to pancreatic cell lines expressing different levels of MUC1, a transmembrane mucin glycoprotein associated with pancreatic ductal adenocarcinoma.

Fiscal year: